Untreated limited scleroderma may turn into systemic scleroderma. Scleroderma is an inflammatory skin lesion that may be caused by hardening or fibrosis of the skin due to genetic, environmental or immune dysfunction factors. Limited scleroderma is usually characterized by the involvement of the skin without internal organ damage, and the lesions can be classified as punctate, plaque, linear, or generalized. If patients with limited scleroderma are not treated in a timely manner, the lesions will gradually expand with the development of the disease, appearing diffuse skin hardening, and may also lead to various organs of the body blood vessels as well as connective tissues to appear sclerosis, hyperplasia and other lesions, such as the gastrointestinal mucosa, the heart and lungs, and ultimately may be transformed into a systemic scleroderma. Patients with limited scleroderma are advised to go to a specialized hospital in a timely manner and under the guidance of a doctor for regular treatment to avoid aggravation of the condition and damage to various organs of the body.