Multiple hepatic cysts, clinically known as polycystic liver, often invade the entire liver, and more than half of the patients are combined with polycystic kidney. According to the distribution of the cysts, the size of the cysts, the compression damage to the liver parenchyma, and the changes in liver function, the hepatobiliary surgeon will evaluate the condition and decide whether surgical treatment is needed. Severe polycystic liver often results in liver failure, which needs to be treated with liver transplantation. Polycystic liver alone has a favorable prognosis, and in no case in a group of patients did polycystic liver disease contribute to their death or deterioration in health. Polycystic liver is associated with polycystic kidneys in more than half of patients, often with genetic factors, and polycystic kidneys can cause kidney failure and death. If the patient is symptomatic, ultrasound-guided aspiration may be considered, but the results are less satisfactory. If the liver function is seriously affected, further treatment should be considered. Precautions: 1, diet is very important for the maintenance of polycystic liver polycystic kidney patients later in life, pay attention to not too hungry, too full, too cold, too hot. Such as high blood uric acid, high blood pressure should be into the low purine, low fat diet, avoid eating animal offal and high fat diet. Later chronic renal failure should pay attention to control the intake of protein in food. 2, polycystic liver polycystic kidney patients daily life activities should avoid strenuous exercise, wear suspenders, do not use the car seat belt around the abdomen, so as to prevent kidney injury due to collision or extrusion, so as not to cause cyst rupture. 3, polycystic liver polycystic kidney patients to avoid kidney infection, avoid taking baths and holding urine, urinate immediately after sexual intercourse, try to avoid urethral catheterization, in case of intracystic infection need to find a kidney specialist to treat, and prolong the use of antibiotics (4-6 weeks). 4, polycystic liver polycystic kidney patients with kidney stones patients should drink a sufficient amount of water every day, so that the amount of urine to reach 2 liters per day, such as still can not be discharged can be considered surgery.