Mild vitamin D toxicity usually resolves itself, while severe toxicity requires medication. Vitamin D is a fat-soluble vitamin. If the poisoning is mild, by drinking more water and then sweating and urinating to enhance the metabolism, the body’s vitamin D content decreases, and the body can independently restore normal function. If the poisoning is severe, it will lead to hypercalcemia, further loss of appetite, heart rhythm disorder, nausea, vomiting, constipation, polyuria, etc., and even cause calcification of soft tissues and impaired kidney function. At this time, we should immediately stop taking calcium and vitamin D, reduce sun exposure, and take hormone therapy, such as prednisone. If you take vitamin D for a long time, once nausea, vomiting, palpitations and other symptoms occur, it is recommended to go to the hospital in time to test the blood calcium concentration, and active treatment.