Leukoaraiosis, also known as Behcet’s disease (BD), is an autoimmune inflammatory systemic disease of unknown etiology, whose basic pathological changes are vasculitis and vascular embolism. The most common clinical signs are recurrent oral ulcers, multiple types of skin damage, arthritis, iridocyclitis, and vulvar ulcers in that order; various organs such as the digestive system, central and peripheral nerves, and the hematologic system can be involved. Early detection of lesions in vital organs and severe vasculitis and vascular embolism and timely treatment are very important to reduce mortality and increase the cure rate. Although the disease can involve all systems and organs, the majority of these patients are still mainly involved in mucous membranes, skin and joints; although the disease can be controlled, it is prone to recurrence and has a long course. Therefore, the Department of Dermatology of Ruijin Hospital has developed a basic treatment plan of controlling acute symptoms with thalidomide (Reactive Stop) and controlling relapses with total leucoside, which has achieved ideal efficacy and reduced the complications caused by long-term glucocorticoid use. Patients with leukodystrophy should pay attention to the following in their daily life and treatment: 1. Develop regular living habits, be in a relaxed mood, and avoid tension and anxiety. 2, oral ulcers to avoid spicy food, rinse your mouth after meals; vulvar ulcers to keep the vulva clean, change underwear daily. 3. Wear sunglasses if you have iridocyclitis. 4.Treat with glucocorticoids and cytotoxic drugs if vasculitis of important organs other than skin and mucous membranes occurs; use anticoagulants as soon as possible when thrombosis occurs. 5.Regular outpatient follow-up and evaluation of related systems when necessary. “Rheumatology and Immunology Specialized Outpatient Clinic”.