In advanced stage of prostate cancer, if only bone metastasis is present, the survival time is usually long, some patients can survive up to 10 years. The specific survival time needs to be combined with the patient’s specific condition and the follow-up treatment to make a comprehensive judgment. Prostate cancer is a type of disease that has a high chance of bone metastasis. Once bone metastasis occurs, it indicates advanced disease and cannot be cured. However, since most prostate cancers are androgen-dependent, reasonable anti-androgen therapy can achieve good results, and most patients can survive for several years with tumors. However, patients who are not sensitive to anti-androgen therapy, or those with combined visceral metastases often have a poor prognosis and a shorter survival time. In conclusion, even if the cancer progresses to an advanced stage with multiple metastases, patients will still benefit from active and standardized treatment. Patients are advised to adjust their mindset and actively cooperate with their doctors to choose a suitable plan for their treatment, which will help improve their quality of life and extend their life expectancy.