Deep headaches are most often seen in brain abscesses, encephalitis, and brain tumors with external radiation to the ipsilateral side. Deep headache is mainly caused by impaired intracranial blood circulation and cerebrospinal fluid circulation as well as increased intracranial pressure, which stimulates cerebral blood vessels and meninges. It should be diagnosed differently from the following symptoms: 1. Superficial headache is often caused by diseases of various organs of the head. Headaches caused by nasal or paranasal sinuses are mostly vague or dull pain and often confined to the sinus area; ear diseases such as otitis media and external ear canal boils can cause ear pain; headaches caused by eye diseases are mostly vague pain near the eyeball and posterior occipital region; headaches caused by refractive errors are often dull pain and heaviness in the frontotemporal region; glaucoma can cause severe headaches, initially confined to the vicinity of the eyeball and accompanied by nausea and vomiting, diminished vision, and increased intraocular pressure. The pain caused by dental diseases is mostly limited to the teeth, and is persistent and boomerang pain. Superficial headache has a good prognosis and often heals itself after the cause disappears; deep headache has a poor prognosis, but the headache can disappear after the primary disease is controlled. 2. Recurrent headache Headache epilepsy refers to recurrent headache as the only manifestation of epilepsy, accounting for 3.8% of epilepsy, mostly seen in children and adolescents, with no significant difference in gender. Some seizures may be preceded by aura, such as emotional irritation, dizziness, nausea, and golden blossoms in front of the eyes. The headache is most common in the frontal region, followed by the temporal region, parietal region, and orbital region. The nature of pulsating pain is the most common, but it also manifests as swelling pain and stabbing pain. 3.Moderate or mild headache Intracranial tumor is also called brain tumor, its etiology is still unknown, the tumor occurs from the brain, meninges, pituitary gland, cranial nerves, cerebral blood vessels and embryonic remnants of tissue, called primary intracranial tumor. If the tumor is metastasized to the skull from malignant tumors in other organs of the body, it is called secondary intracranial tumor. Brain tumor is the disease that triggers moderate or mild headache. 4.Epileptic headache Epileptic headache, pain is more intense, mostly deep distension, blast-like pain, often accompanied by vomiting, signs of neurological damage, convulsions, disorders of consciousness, mental abnormalities and even changes in vital signs to varying degrees. 5.Intracranial headache Intracranial headache refers to the headache caused by traumatic cerebrospinal fluid fistula or lumbar puncture, which causes excessive leakage of cerebrospinal fluid from the puncture site to the outer spinal cavity, resulting in a decrease in pressure in the spinal canal and pulling down of pain-sensitive tissues in the posterior cranial fossa. Headache is common after lumbar puncture. 6.Functional headache Functional headache is also called psychogenic headache. It mainly includes neurasthenia, hysteria, post-concussion, depression, and menopausal syndrome. The headache is often recurrent, with mainly distension, variable location, vague nature, and no certain pattern, often with a cap-like tightening sensation at the top of the head, or pulling pain from the forehead to the neck, and a feeling of many small insects burrowing around the top of the head. In addition, it is often accompanied by dizziness, fatigue, dreaminess, insomnia, memory loss, lack of concentration and other symptoms, with a long course and intermittent attacks. 7.Migraine Migraine is a kind of recurrent throbbing headache, which is one of the “big” headache types. It often has aura of flashing light, blurred vision and numbness of the limbs before the attack, and the pain on one side of the head appears for a few minutes to about an hour, and gradually increases until nausea and vomiting appear, and the headache is relieved in a quiet, dark environment or after sleep. The headache may be accompanied by neurological and mental dysfunction before or during the onset of the headache. It is also a progressively worsening disorder that usually occurs with increasing frequency. According to studies, migraineurs are more likely than usual to have localized brain damage, which can lead to stroke. The more frequent their migraines are, the larger the area of the brain that will be damaged.