Duodenal ulcer stage a1 is more serious, and duodenal ulcer is divided into active, healing and scarring stages. The stage a1 duodenal ulcer refers to the first stage of the active phase, in which the ulcer, the mucosa is congested and edematous and covered with thick yellow moss, which can cause bleeding when touched, and even acute abdominal conditions such as perforation can occur in severe cases. Therefore, duodenal ulcer stage a1 is more serious and should be treated actively. The main clinical treatment includes anti-H. pylori treatment, inhibition of gastric acid secretion, protection of gastric mucosa and so on. If H. pylori is found, standard anti-H. pylori treatment should be administered. Acid suppressants such as omeprazole, rabeprazole, pantoprazole, etc. should also be taken. It should be accompanied by gastric mucosal protective agents, such as bismuth aluminate, colloidal bismuth, etc. The course of treatment should usually be 6-8 weeks, and attention should be paid to a light diet with no spicy and stimulating foods.