1. Some exposures such as lead, mercury, arsenic, (automotive) hydrocarbons, cadmium, amoebicidal fumigant vaporizers have been reported. As well as 2-bromopropane can damage spermatogenic function. 2, a variety of agricultural pesticide exposure is also associated with semen quality damage. 3, Organic solvent-exposed populations are prone to elevated FSH levels and impaired semen parameters compared to non-exposed populations. 4. Patients highly exposed to heavy metals (e.g., lead, mercury) should have their serum levels tested.