Acne is a manifestation of acne, and the causes of acne on the face are complex, mainly related to follicular factors, bacterial infection, dietary factors and endocrine disorders, but the disease varies greatly among individuals and may be caused by a variety of factors. 2. Bacterial infection: Bacteria on the skin surface, such as Propionibacterium acnes, can hydrolyze triglycerides in sebum, and the free fatty acids produced by them can stimulate epithelial hyperplasia and hyperkeratosis at the opening of the sebaceous glands of hair follicles, thus manifesting as acne. Bad habits such as touching the skin on the face several times with both hands and not changing the pillowcase frequently can cause bacterial infection, resulting in the continuous appearance of acne on the face of patients; 3. 4, endocrine disorders: long-term oral androgenic drugs, hyperadrenocorticism, etc. can lead to high levels of androgens in the patient’s body, causing the sebaceous glands on the face to increase, sebum secretion increases, and sebum provides the material basis for the growth of parasitic bacteria in the hair follicles, resulting in the continuous appearance of acne on the patient’s face.