Patient: diagnosed by the doctor on October 9: epigastric distention and pain, nausea and vomiting, liver is 15CM hard under the sword, pressure pain (+), surface is still flat. Two hypoechoic masses were seen in the left outer lobe of the liver, measuring 5.7×4.6CM and 4.1×4.7CM respectively, with poorly defined borders and uneven internal echogenicity. The intrahepatic ductal structure was clear, the left lobe was vascularly compressed, and the internal diameter of the portal vein trunk was about 0.7 CM. The gallbladder was about 4.5 CM×2.1 CM, with an unclear outline and irregular thickening of the wall, about 0.6 CM at the thicker part, and the lumen did not show any dilatation of the intra- and extrahepatic bile ducts. Multiple hypoechoic nodules were seen in the retroperitoneum, the larger of which was 2.0×0.9 CM in size. CDFI: A little blood flow signal was seen within the above liver mass, arterial blood flow spectrum RI=0.66, and portal venous blood flow velocity was in the normal range. Ultrasound suggests: substantial occupying lesion in the left lobe of the liver, liver ca possibility of mild fatty liver Retroperitoneal lymph nodes enlarged gallbladder no significant abnormalities No effective treatment is available in our city hospital. I hope you can guide how to treat it! Li Baoguo, Department of Interventional Therapy, Tianjin Cancer Hospital: The patient lacks pathological diagnosis and the clinical stage is backward. In view of the patient’s young age, it is recommended to take measures to control the progress as soon as possible. 1.Obtain pathological diagnosis 2.Embolization of blood supplying artery of liver tumor 3.Cryotherapy to reduce the volume of tumor if necessary 4.Molecular targeting drug maintenance, such as sorafenib, etc. 5.Anti-cancer drugs