The swollen lymph nodes in the abdomen of children can be caused by a variety of reasons, and it is not possible to determine whether the symptoms are leukemia based on this symptom alone. There are many clinical causes of swollen abdominal lymph nodes in children, but they are mostly seen in benign abdominal hyperplasia. If they are not accompanied by other clinical symptoms, no special treatment is usually needed and regular observation is sufficient. If a child has swollen abdominal lymph nodes with significant abdominal pain, it may be due to acute mesenteric lymphadenitis and requires treatment with antibacterial drugs. If multiple lymph nodes in the abdomen are significantly enlarged and fused with each other, lymphoma and lymph node metastasis from malignant gastrointestinal tumors in the abdomen are considered, which requires further improvement of relevant examinations and symptomatic treatment. In addition, patients with leukemia may also have swollen lymph nodes, most notably in the groin, especially in children with acute lymphoblastic leukemia, but they may be accompanied by other manifestations such as anemia, and need to be diagnosed clearly by puncture biopsy or pathological examination. Children with swollen abdominal lymph nodes need to go to the pediatric surgery department of a regular hospital in time to be examined by a professional doctor and treated symptomatically after a clear diagnosis.