1.Minimally invasive surgical treatment of diabetic foot, namely “percutaneous peripheral angioplasty”, is an emerging and efficient treatment method for diabetic foot adopted internationally. Simply put: “It is to puncture at the root of the thigh (2~3mm trauma), then insert a catheter with a balloon into the lumen of the target artery, fill the balloon after reaching the lesion site, dilate the narrowed section of the vessel, restore the blood supply to the distal part of the lower extremity, and achieve the treatment purpose. With the development of minimally invasive interventional materials and techniques, it is possible to open all the occluded lower limb vessels, including the arteries of the dorsum of the foot, thus achieving the purpose of directly improving the blood supply to the lower limbs, on which basis other treatment measures can achieve good therapeutic results.” 2.Vascular reconstruction surgery: the most commonly used one is vascular bypass diversion surgery. In other words, an autologous or artificial vascular bridge is built between the normal blood supplying arterial segment and the distal non-stenotic arterial segment of the diseased vessel to improve the blood supply to the distal limb. 3.Autologous stem cell transplantation: Autologous bone marrow stem cell transplantation is used to treat lower limb ischemia.