Now we are familiar with diabetic foot, but if we associate hyperbaric oxygen with diabetic foot, we may not know what the connection is. Many hospitals now use hyperbaric oxygen as one of the methods for diabetic foot, but what are the clinical results? What is hyperbaric oxygen? As the name implies, hyperbaric oxygen therapy is the breathing of pure oxygen in an environment with more than one atmosphere of pressure, allowing the patient to inhale more oxygen content. What are some of the principles of hyperbaric oxygen therapy? Hyperbaric oxygen promotes microcirculation in the foot by increasing blood oxygen content, reducing blood viscosity, increasing blood flow rate, improving ischemia and hypoxia in distal limb tissues caused by vascular occlusion, effectively promoting oxygen absorption in the diabetic foot ulcer wound site, prompting granulation tissue proliferation and epithelial cell growth, and accelerating ulcer wound healing. Hyperbaric oxygen therapy can increase the partial pressure of blood oxygen, so that oxygen can be delivered to the oxygen-deficient tissues in the distal part of the limb, and cause vasoconstriction and reduce exudation, thus reducing the edema of foot tissues. Hyperbaric oxygen therapy can increase the bactericidal ability of white blood cells and improve the autoimmune function, thus providing an effective antibacterial effect and controlling the infection of diabetic foot. Hyperbaric oxygen therapy increases the speed of sensory and motor nerve conduction in diabetic foot patients, repairs damaged nerves and reduces sensory impairment in diabetic foot patients, and also enhances the sensitivity of tissues to insulin and improves glucose metabolism in diabetic patients. Third, what is the effect of hyperbaric oxygen? If we follow the above statement, hyperbaric oxygen should be a good method to treat diabetic foot, but I think most of them are still theoretical effects. For example, even if the oxygen content in the blood is high enough, one of the main causes of wound infection in most diabetic foot patients is vascular inaccessibility, in which case the blood flow is slowed down or completely blocked, and it is impossible for oxygen to increase the oxygen saturation of the lesion, so I think it is not particularly helpful for wound healing. For diabetic foot treatment, the first priority is to control infection and promote wound healing, so a targeted treatment plan must be developed for each cause, such as lowering blood glucose and blood lipids, improving circulation in the lower extremities, cleaning inflammatory necrotic tissue, applying topical Chinese ointment, etc. However, we cannot say that hyperbaric oxygen is useless, but it cannot be used as the main treatment method, but only as an aid. Our hospital is currently using a combination of Chinese and Western medicine open therapy, the treatment process does not need to do hyperbaric oxygen therapy to patients, but also to achieve the desired effect, which also gives patients and families to reduce a certain economic burden.