Intrahepatic cholestasis of pregnancy is a complication characterized by pruritus and jaundice that occurs in late pregnancy. It mainly affects the fetus and increases perinatal morbidity and mortality. Pruritus is often the first symptom in patients with intrahepatic cholestasis in pregnancy, most often appearing at 28 to 32 weeks of gestation, but also starting as early as 12 weeks. The degree of itching varies, with the palms of the hands and feet being the main sites, but no skin lesions appear, and in severe cases, the whole body itches, and some people can not even sleep and need to terminate the pregnancy. Postpartum symptoms subside rapidly, mostly disappearing 2d after delivery, a few disappear in about 1 week, and may recur in another pregnancy. The cause of itching may be biliary stasis, bile salt stimulation of sensory nerve endings. At present, there is no ideal drug for the treatment of this disease, generally can use liver protection drugs, such as liver tylenol, vitamins, etc., and routine supplementation of vitamin K1, the symptoms of obvious people can be considered to use cholestyramine, Phenobarbital, Semtex, dexamethasone and so on. Chinese medicine believes that this disease belongs to the “pregnancy body itch” category, the etiology of the disease is mainly for the yin deficiency and blood dryness, dampness and heat inside. On the treatment of yin deficiency and blood dryness nourishes blood mainly, with nourishes kidney and nourishes yin, such as danggui dihuang drink ( ” evidence treatment quasi-jiao ” ) combined with two to pill ( ” medical prescription set explanation ” ), the prescription is as follows: danggui 10g, chuanxiong ligusticum 10g, white peony 15g, raw dihuang 10g, fengfeng 10g, jingxiao 10g, huangqi 20g, licorice 6g, shouwu 15g; Dampness-heat internal impregnation purges the heat and dispels dampness mainly, with strengthens the spleen and nourishes blood, such as dan gardenia The free dispersal (“Xue’s medical case”) and three things Yin Chen Tang (“the evidence treatment quasi”), the prescription medicine is as follows: Dampi 15g, gardenia 6g, Chaihu 9g, Angelica sinensis 9g, Poria 15g, Atractylodis Macrocephalae 15g, Paeonia lactiflora 15g, Mentha piperita 6g, sizzling licorice 3g, simmering ginger 9g. the above traditional Chinese medicines pay attention to the treatment of disease and the fetus, can achieve better curative effect.