Based on international literature and domestic experience, China has developed the latest clinical diagnostic criteria, which require that the clinical diagnosis of HCC can be established when both (1)+(2)a or (1)+(2)b+(3) of the following conditions are met: (1) evidence of cirrhosis and HBV and/or HCV infection (HBV (2) typical imaging features of HCC: simultaneous multi-row CT scan and/or dynamic contrast-enhanced MRI showing rapid hepatic occupancy in the arterial phase (Arterial hypervascularity) and rapid washout in the venous or delayed phase (Venous or delayed phase phase washout ). (1) If the diameter of liver occupancy is ≥ 2 cm, one of the two imaging examinations of CT and MRI shows that the liver occupancy has the characteristics of hepatocellular carcinoma mentioned above, HCC can be diagnosed. (3) Serum AFP ≥ 400 μg/L for 1 month or ≥ 200 μg/L for 2 months, and other causes of elevated AFP can be excluded, including pregnancy, germline tumors of embryonic origin, active liver disease and secondary hepatocellular carcinoma.