Misconceptions in Liver Disease Patient Visits

Patients are prone to misunderstandings in the consultation process: Misunderstanding of hepatitis infectious. Viral hepatitis causing chronic liver damage is mainly hepatitis B, hepatitis C, and hepatitis A, hepatitis E is a cause of acute hepatitis, basically will not be chronic, hepatitis A and E spread through the digestive tract, while hepatitis B, hepatitis C through the blood, bodily fluids, mother-to-child vertical, traumatic medical equipment, etc., the daily work or life contact, such as working in the same office (including sharing office supplies such as computers), shaking hands, Daily work or life contact, such as working in the same office (including sharing computers and other office supplies), shaking hands, hugging, living in the same dormitory, eating together, sharing toilets and other contacts without blood exposure generally do not spread hepatitis B and C. Therefore, for people with HBsAg(+) or chronic hepatitis C, first of all, they should be clear about the way of transmission of their own disease, do not have an inferiority complex and isolate themselves from their family and friends, and secondly, they should educate people around them to have correct medical knowledge and not to discriminate against people with chronic hepatitis B or C. A large number of facts have proved that one of the husband and wife has slow hepatitis B or C, but the other one has not been infected even after decades of living with them. As long as there are scientifically correct means of protection and avoidance of blood exposure, one will not be infected. This is also the scientific basis for the Ministry of Health’s decision not to allow hepatitis B-related indicators to be checked during the physical examination for entry into the workforce. Sun Changyu, Department of Infectious Diseases, First Affiliated Hospital of Zhengzhou University Myth 2: Misunderstanding of diagnosis and testing. Some chronic hepatitis B patients and even non-liver disease specialist medical personnel, there is a common understanding that “small triple sun” is good and “big triple sun” is not good, this is a completely wrong idea. Whether it is “major triple positive” or “minor triple positive”, there are chronic hepatitis B carriers and chronic hepatitis B patients, if it is a carrier, it means that the condition is relatively stable, basically there is no obvious liver damage, can withstand normal work, study tasks; if it is a chronic or active or cirrhosis patients, then it is not a good idea to have a chronic hepatitis B carrier. active or cirrhotic patients, treatment is necessary. The so-called big and small triple positive refers to the hepatitis B immunity index e antigen positive or e antigen negative, positive for big triple positive, negative for small triple positive, it only reflects the body’s hepatitis B immunity marker status, does not represent the severity of the disease or the size of the contagious. The severity of the disease depends on the indicators of liver function and liver imaging, pathology and other indicators, and the infectiousness depends on the viral load in the blood. Therefore, many of the carriers in patients with triple III do not need treatment for the time being, but should be regularly reviewed, while patients with triple III should be analyzed on a case-by-case basis, first of all, to determine whether the virus is positive (i.e., whether HBV-DNA is positive or not), whether the liver function is normal or not, and whether there is liver fibrosis or even cirrhosis in the liver imaging test. If the liver function is abnormal, DNA-positive “small triple sun” needs to be actively treated, and should not delay the treatment with the fact that it is “small triple sun”. Myth 3: Misconceptions about hepatitis treatment. The most common misconception about the treatment is the lack of understanding of the importance of antiviral treatment and the course of treatment. The reason why chronic hepatitis develops into chronic is that the virus can not be cleared by the body’s immune system and lurks in the body for a long time, repeatedly destroying the liver cells and leading to chronic activity or even hepatic fibrosis and liver cirrhosis. When the virus destroys the liver cells, the liver cells are necrotic and cleavage, and the various enzymes in the cytosol or mitochondria are released to the blood, which causes the elevation of the enzyme level in the blood, such as alanine aminotransferase, glutamic oxalate aminotransferase, and so on. The elevation of enzymes reflects the damage of hepatocytes, and the enzyme-lowering treatment is a symptomatic treatment. The reduction of aminotransferase to normal is not equal to the cure of chronic hepatitis, and the virus is still lurking in the hepatocytes, which may cause obvious liver damage and elevation of aminotransferase at any time. Therefore, antiviral treatment is the most important treatment of all kinds of treatment. Only by suppressing or even eliminating the virus can we solve the phenomenon of repeated damage to hepatocytes, repeated hepatitis activities, and repeated elevation of aminotransferases. However, due to the difficulty of antiviral treatment and medical limitations, there is no drug that can completely eliminate the virus in a relatively short period of time. At present, internationally and domestically recognized effective anti-hepatitis B virus drugs are mainly two categories: interferon and nucleoside (acid), these two types of drugs are also relatively long treatment time. Interferon treatment for six months to two years, nucleoside (acid) class treatment for three to five years or even longer. Long-term drug therapy is required for patients with decompensated cirrhosis. Therefore, for the treatment of chronic hepatitis B, it is necessary to establish the basic concept of antiviral treatment as long as there are indications, but also to establish the concept of long-term treatment, and the concept of sustained battle with the virus, and must not be superstitious “charlatan” and some false advertisements of the so-called “how long australian resistance to conversion of Yin “The actual fact is that the actual HVAC is a lot more than just an HVAC. There may be “special cases” and “individual cases” where HBsAg has become negative around you, but it is very likely that it is acute hepatitis B. HBsAg is a self-limiting disease. Acute hepatitis B is a self-limiting disease, the natural rate of reversal of more than 90%, while slow hepatitis B surface antigen is difficult to negative, the natural rate of reversal of 1 to 3%, is the need for long-term treatment. Myth 4: Insufficient knowledge of regular review of chronic hepatitis B carriers or patients. In clinical work, many hepatologists often see the first diagnosis of cirrhosis or liver disease patients, has developed into an advanced stage is difficult to treat, this phenomenon is relatively common. Through inquiring about the medical history, we found that these patients knew that they were HBsAg (+) carriers, and did not regularly review or seek medical treatment, often citing “busy at work” and “no abnormal feeling” as the reason for not having regular checkups, and once they “had a feeling”, they did not know that they were HBsAg (+) carriers, but they did not know that they were HBsAg (+) carriers. “Once you have the feeling, the disease is in an advanced stage, which is very unfortunate. How to avoid this kind of tragedy, only to strengthen the patient’s self-management, regular review, and always understand the changes of their own condition is the best means, and can not be “feel, have discomfort” as the reason for consultation. Most of the disease progress of chronic viral hepatitis is caused in the case of “no feeling”, the virus lurks in the liver cells, and quietly causes liver cell damage, fibrosis and even cirrhosis in the accumulation of time. Therefore, patients and specialists should closely monitor this process and use antiviral drugs in a timely manner to prevent the virus from causing quantitative changes to qualitative changes. For patients who have already used antiviral therapy, it is more important to have regular checkups and establish a good doctor-patient relationship with doctors. Through regular review of liver function and virological indicators, observe the efficacy of antiviral therapy, timely detection of adverse reactions to antiviral therapy, such as the side effects of interferon therapy and the occurrence of drug resistance to nucleoside oral medications, timely adjustments and changes in the treatment program, to fundamentally prevent the progression of the disease, to improve the quality of life, and to prolong the life of the purpose. Myth 5: Give up the requirement of reproduction because you are HBsAg (+) carrier. It is also common for some chronic hepatitis B virus carriers to give up their reproductive requirements for fear of infecting their children, and even for some young people to refuse to talk to someone or get married. In recent years, with the popularization of the vaccine, the HBsAg (+) carrier rate of newborns and children has decreased significantly, and the success rate of mother-to-child interruption is more than 90%. Therefore, HBsAg (+) carriers can give birth to healthy babies like normal people as long as they have the conditions to have children, but they must remember to go to obstetrics and gynecology and liver disease specialists for consultation and mother-to-child interruption strategies.