After liver failure, due to severe necrosis of liver cells, liver function decreases dramatically, most patients have a poor prognosis, and there is a big difference in how long they can live, if no effective treatment, they may die within a few days, and if liver transplantation is performed, they can even live for 20-30 years. The liver has the functions of synthesis, detoxification, metabolism, secretion, biotransformation, and immune defense, etc. The severe damage that can be caused by liver failure results in a large number of necrotic hepatocytes, leading to severe impairment or loss of compensation of the aforementioned liver functions. Patients may exhibit symptoms such as extreme fatigue, loss of appetite, abdominal distension, nausea, vomiting, and altered mental status, and the disease progresses rapidly, is difficult to treat, is expensive to treat, and has a poor overall prognosis. Liver failure needs to be prevented from the cause, the existence of chronic hepatitis virus infection patients, need to regularly check the liver function and hepatitis B virus replication status, do not stop taking medication without authorization, alcoholics must adhere to the cessation of alcohol.