In addition to prevention-oriented osteoporosis, early treatment-oriented is also necessary, the earlier the better, but when to start treatment is not too late, basic treatment: one hour of sunshine every day, exercise for at least half an hour, a nutritious diet, a glass of milk every day, ensure sleep, adults 45 years old need a daily supplement of calcium 800 – 1200 mg. Despite the early prevention, the decrease of bone density and fragility fracture is still inevitable clinically, so drug therapy is still needed to control the development of the disease, the current commonly used drugs are: 1, bone mineral promoters, calcium therapy and vitamin D derivatives. 2. Bone resorption inhibitors: bisphosphonates (Fosamax), calcitonin, estrogen replacement therapy. 3.Bone formation promoting drugs: parathyroid hormone, fluoride. 4.Chinese medicine treatment.