The leukemic state affects the body’s immunity so much that controlling the infection is often a mirrored pipe dream if the leukemic state is not reversed. In other words, if you want to completely control the infection, you must find ways to schedule chemotherapy as early as possible in an attempt to remit the acute leukemia as soon as possible. In TCM terms, leukemia is the root cause and infection is the symptom, and you need to treat both the symptoms and the root cause, not the symptoms but not the root cause. On the contrary, if you wait for the infection to be controlled before chemotherapy, you will end up losing the opportunity for chemotherapy. The general chemotherapy regimen and timing will vary in the presence or absence of infection.