The survival time after platelet depression is not generalizable and depends on the severity of the disease, individual condition, treatment and comorbidities of the patient. The normal range of platelets is (100-300)×10^9/L. If the platelets are depressed due to viral infections, toxic substances, etc., the patient’s symptoms will improve when the cause is removed. If it is caused by acute leukemia, the patient’s life will be in danger within a few months if treatment measures are not taken in time. If the platelet count is below 80×10^9/L, the patient’s own hemostatic function is not impaired and therefore not life-threatening. If the platelet value is below 50×10^9/L, bleeding may occur easily during falls, bumps, and surgery, and may be life-threatening. If platelets are below 30×10^9/L, spontaneous bleeding may occur, and in severe cases, gastrointestinal and intracranial bleeding may occur, which may seriously threaten the patient’s life. Patients are advised to consult the hematology department as soon as possible to find the cause of the discomfort, treat the cause, and recover as soon as possible.