Retrograde ejaculation means that during sexual intercourse, although the man can have orgasm and the feeling of ejaculation, the bladder neck is open and the semen goes through the “back door” and all flows backwards from the posterior urethra into the bladder without ejaculating from the urethra. The causes of retrograde ejaculation are many and complex, including congenital and acquired factors such as local inflammation, urethral stricture, surgical damage to the bladder sphincter, and medications (reserpine, dextran). The inability to sow the “seeds” of fertility causes his wife’s infertility. Although on the surface, retrograde ejaculation and non-ejaculation patients both appear to have no semen emission during intercourse, they are two completely different things: non-ejaculators often lack orgasm, no semen is ejaculated after sex, and no evidence of the presence of sperm can be found in centrifuged urine; retrograde ejaculators have orgasm, and the urine ejaculated after sex contains a large amount of sperm. For retrograde ejaculation, as long as the condition of “red light at the front door” and “green light at the back door” is changed, the normal ejaculation during sexual intercourse can be restored naturally. The direct treatment of retrograde ejaculation mainly includes etiological treatment and symptomatic treatment. Even if the clinical results of some retrograde ejaculation patients are not satisfactory, in order to solve the patient’s urgent fertility problem, the collection of sperm in the urine can be considered for artificial insemination or in vitro fertilization treatment.