There is no specific antidote for paraquat poisoning, so it is necessary to remove paraquat that has not been absorbed into the bloodstream as early as possible, and take first aid treatment such as inducing vomiting and gastric lavage. And give general treatment, drug treatment or blood purification and other related treatment, in order to reduce the absorption of paraquat and promote the excretion of poison. 1. First-aid treatment: actively detach the poison, immediately take off the contaminated clothes when the skin is contaminated, and rinse with flowing water and soap water for 15 minutes; when the eyes are contaminated, immediately rinse with water for 10 minutes; induce vomiting and gastric lavage for those who have been poisoned by oral intake immediately. 2. General treatment: for patients with respiratory failure whose partial pressure of oxygen in blood gas analysis is less than 40mmHg and oxygen saturation is less than 70%, it is necessary to actively give them oxygen therapy, and give them ventilator-assisted breathing if necessary. 3. Drug treatment: glucocorticoid is the main drug for treating paraquat, and methylprednisolone is preferred; reduced glutathione can effectively counteract the peroxide damage of paraquat. 4. Blood purification: hemodialysis is mainly applicable to patients with paraquat poisoning with renal function injury; blood perfusion should be carried out as soon as possible after paraquat poisoning, and the effect is good within 2~4 hours. When paraquat poisoning occurs due to various reasons, it is necessary to consult the doctor in time and standardize the treatment under the doctor’s guidance, and it is important not to use drugs arbitrarily and delay the time of treatment.