Glucocorticoids have potent anti-inflammatory and immunosuppressive effects that can reverse the disease and are the basic drugs used in the treatment of SLE. However, hormones also often induce diabetes, osteoporosis and aseptic osteonecrosis, ulcer disease, and complicating bacterial and mycotic infections. So much so that lupus patients have a love-hate relationship with hormones. Chinese medicine can both prevent or reduce the atrophy of the adrenal cortex and promote the atrophied adrenal cortex to restore its normal secretory function, and it can improve the immune function of the body, enhance resistance and prevent infection. Chinese medicine believes that hormones are exogenous “pure yang” products, and after acting on the human body, yin and yang will be imbalanced, and yin and yang will grow and grow from kidney yin deficiency to kidney yang deficiency to both yin and yang deficiency. Under the principle of TCM diagnosis and treatment, adjusting yin and yang can restore the normal function of the body. Chinese medicine has a significant improvement effect on the side effects induced by hormones. If hormones are used for a long time, it is easy to weaken the immunity of the body and aggravate the disease. When the use of hormones cannot be stopped or the dosage of hormones cannot be reduced for the time being, Chinese medicine is often used to enhance the immunity of the body, such as ginseng, astragalus, atractylodes, rehmannia, angelica, etc. If hormone induced gastrointestinal damage, Si Jun Zi Tang and Ginseng and Atractylodes are often used to strengthen the spleen and eliminate food. Long-term use of hormones is likely to cause osteoporosis and fracture. According to Chinese medicine, hormones deplete the kidney essence, leaving the essence empty and the bones deprived of nourishment, resulting in osteoporosis, so the treatment adopts Jin Kui Kidney Qi Pill and Dou Wu Xie Sheng Tang. If hormones damage the blood system, the skin may be wrong, and the tongue may have petechiae or bruises, so the treatment is to invigorate the blood and open the ligaments, such as Tao Hong Si Wu Tang and Blood Mansions and Blood Stasis Soup.