SARS” in 2003, “human highly pathogenic avian influenza” in 2005, “influenza A (H1N1)” in 2009, plus the onslaught of “Hand, foot and mouth disease”, infectious diseases are coming one after another; are we ready? These outbreaks of new and common infectious diseases are not only a serious challenge to the medical community, but also a serious threat to the survival of humanity. The threat of infectious diseases to humans is not only the disease itself, the 2003 “SARS”, 2005 “human highly pathogenic avian influenza”, 2009 “H1N1 influenza A The impact of the “SARS” outbreak in 2003, the “highly pathogenic human avian influenza” in 2005, and the “H1N1 influenza A” in 2009 on the global economy and social security issues are still vividly visible. Global health organizations and even the entire human community chanted the slogan of fighting to the death against infectious diseases! But new infectious diseases and traditional infectious diseases continue to make their unrelenting appearance in waves of powder. Our country has been tirelessly investing a lot of human and material resources in the infrastructure and scientific research of infectious disease control, and has achieved remarkable results! But is it enough? Have we developed a sound system for infectious disease control? Do we have the ability to control outbreaks or pandemics of infectious diseases in a timely manner? Have we mastered the pathogenesis and treatment of traditional classical infectious diseases? The answer is no! HFMD is not a new infectious disease, and we have been pulling banners in hospitals week after week, year after year: “timely control of the epidemic, contributing to local construction and stability”. But the HFMD epidemic has not been extinguished as a result. It is reasonable to say that the contagiousness of HFMD is not as strong as the contagiousness of respiratory infectious diseases such as SARS and Influenza A. How effective is our prevention and control work? I do not dare to say whether we should adjust the control measures. The current situation of patient consultation is not conducive to the prevention and treatment of one or two situations: 1, hand, foot and mouth disease prevention and treatment work to the pediatric department of general hospitals, hand, foot and mouth disease clinic and general pediatric outpatient clinic with the same in and out. It is recommended to build a special independent hand, foot and mouth disease outpatient clinic. 2, the basic hospital does not have the ability to receive and treat, diagnosis and treatment, patients whether serious or not to run to tertiary hospitals, along the way referral and lead to the spread of infection. It is recommended to strengthen operational training and infrastructure to provide local consultation and treatment conditions for children with HFMD and avoid excessive and unnecessary referrals. 3. The pediatrics department of general hospitals is not a specialized pediatric hospital, and there are few specialized infectious disease pediatric wards. It is recommended that the local construction of infectious disease hospitals routinely set up pediatric infectious disease wards and specialized prevention and control teams, so that the prevention and treatment of HFMD is regularized, formalized and specialized. Some remote counties and even local (state) cities do not have special infectious disease hospitals, which should be worth paying attention to. 4, hand, foot and mouth disease cases are referred too arbitrarily, the provincial children’s hospital is overcrowded, most of the public transport or private car referrals. This poses a great challenge to prevention and control. It is recommended that a standardized referral process be developed, for example, no referral is recommended for mild cases, and serious cases are transported by professional negative pressure ambulances.