Introduction to the long protocol Applicable population: Generally speaking, patients younger than 40 years old with basal FSH <10>8, choose the long protocol, in which for patients with polycystic ovary syndrome, the double pressure long protocol is used; the long protocol is the most common and classic one in IVF ovulation promotion, which is widely used due to its good controllability and high pregnancy rate. In other special cases, such as low ovulation rate in the previous IVF boosting, low ovarian response, etc., patients need to enter the pre-cycle specialist clinic again to draw up a plan. Treatment process: The long luteal phase protocol starts 1 week after ovulation of the previous menstrual cycle, i.e. on the 21st-22nd day of menstruation of a patient with normal menstrual cycle, with blood test for progesterone and vaginal ultrasound on the same day; if the oral administration of Mafulone starts on the 5th day of menstruation, the oral administration of Mafulone will be until the 17th tablet, with vaginal ultrasound on the same day, and the patient will enter the cycle after meeting the conditions. The first stage of the long protocol after entering the cycle is hyporegulation, starting from the day of entering the cycle, short-acting GnRH-a preparation (treprostinil) 0.05-0.1mg/day is injected for 14 consecutive days, and after 14 days, if the pituitary hyporegulation criteria are met (LH <5mIU/ml, FSH <5mIU/ml, E2 <30pg/ml, maximum follicle diameter ≤8mm, endometrial thickness ≤ 5 mm), Gn initiation. GN initiation is the controlled ovulation phase, where ovulation drugs are applied to promote follicle growth, usually about 10-12 days, but the specific application time depends on individual follicle growth, follicle growth to 17-18mm in diameter after the chorionic gonadotropin trigger, that is, "night injection", 36 hours after the night injection for egg retrieval surgery. Caution: 1. Patients on the long protocol should use contraception in the month of the cycle. 2. If you have cold, diarrhea or other illnesses during the period of down regulation and ovulation promotion, you should be actively treated in the corresponding internal medicine clinic and inform your doctor to avoid the application of drugs that may affect you during the IVF treatment cycle.