The occurrence of irritability at the slightest thing is considered to be possibly caused by mania or anxiety disorder. Patients often have mood control disorders such as anger at the slightest thing, irritability, and large mood swings. In addition, it may also be depression, insomnia, schizophrenia, personality disorders, dementia, hyperthyroidism and other causes of irritability. 1, depression: patients inward, nervous emotional state, as well as genetics, unexpected events stimulation and other factors, may suffer from depression, with low mood, loss of interest and pleasure, reduced attention, impulsive irritability and other typical symptoms, some of the more serious patients Some of the more serious patients may also have suicidal tendencies. In addition, maternity is also a high prevalence group of depression, there are irritability, irritability, frustration and other emotions; 2, insomnia: long-term poor quality of sleep, insufficient sleep time and other sleep disorders, can seriously affect the normal life of patients, learning, not only memory loss, slow thinking and other problems, there will be things like easy to get angry, irritable mood regulation abnormal; 3, schizophrenia: belongs to a more serious Patients often have a series of clinical manifestations such as excitement, irritability, hallucinations, hallucinations, etc. In serious cases, mental decline and mental disability may be complicated; 4. Personality disorders: mainly due to genetics, social environment, brain damage and other factors, patients have deviations from normal personality attributes and behavioral patterns, with manifestations such as paranoia, impulsiveness, easy to argue, compulsion, and anger; 5. Dementia syndrome: often occurs in the elderly population, there are often mental abnormalities, behavioral disorders, including screaming, irritability, aggression, etc., at this time, family members should avoid letting patients go out alone; 6. Hyperthyroidism: referred to as hyperthyroidism, the patient’s body organs will appear abnormal performance, so it will affect the nerves, triggering irritability, irritability. In addition to the above disease factors, the patient’s irritable personality is also related to factors such as upbringing atmosphere, family education, and long-term alcohol consumption. In addition, if patients suddenly stop taking lipid-lowering drugs such as simvastatin, resulvastatin, pravastatin, etc., it will affect the serotonin level in the brain, which will easily trigger irritability and irritable mood. Therefore, you can promptly inform your doctor if you can gradually reduce the dosage or the number of times you take the drugs.