Liver nodules are lesions with abnormal proliferation of hepatocytes, structural disorders of liver lobules, and partially accompanied by proliferation of fibrous tissue, which can generally be detected by imaging. The pathogenic mechanisms are complex and diverse, and whether they are serious or not depends on the nature of liver nodules. Usually, the types of liver nodules are shown as follows: I. Benign lesions 1. Regenerative hyperplasia of liver nodules: the incidence is not high. Mainly seen in elderly patients, patients are mostly accompanied by rheumatoid arthritis, blood disorders, etc. Generally the nodules can be surrounded by no fibrous tissue. Most patients are not seriously ill, but individual patients may develop portal hypertension. Occasionally, hepatocellular carcinoma can occur, and regular review is usually required. There is a lack of more effective treatment methods, mainly symptomatic treatment for portal hypertension and shunt or dissection surgery according to the condition; 2. Focal nodular hyperplasia of the liver: it is a benign nodular lesion, patients usually have no conscious symptoms, and those with larger nodules may experience discomfort in the upper abdomen and liver area, and in rare cases, the nodules can bleed. Mild cases can be treated conservatively with close observation; severe cases require surgery. The disease generally has no tendency of malignancy and good prognosis, so it is relatively not serious. 3. Hepatic adenoma: It is a benign tumor of the liver, the condition is mostly not serious, mostly related to young women taking birth control pills. There is no obvious clinical discomfort, but only incidentally found in imaging examination, and individual patients may have intratumoral bleeding or ruptured bleeding. Patients can achieve a better prognosis after surgical excision, and generally do not have malignant transformation or recurrence. 2. Anisotropic hyperplastic nodules or malignant lesions 1. Anisotropic hyperplastic nodules: including low-grade anisotropic hyperplastic nodules and high-grade anisotropic hyperplastic nodules. Low-grade heterogeneous hyperplastic nodules are relatively less serious. If you have hepatitis B, you need liver-protective therapy and immunomodulatory therapy, as well as treatment of cirrhosis and attention to regular review. High-grade heterogeneous hyperplasia nodules are precancerous lesions, which are relatively serious and should be removed surgically. 2. Liver cancer: patients do not necessarily have clinical symptoms, but mostly have a history of chronic liver disease, and their condition is relatively serious, and they usually take partial liver resection, liver transplantation, radiofrequency ablation, local embolization chemotherapy of hepatic artery, etc.