Perimenopause includes the period between the transition to menopause and one year after menopause. From this period, a woman’s ovaries begin to fail and she gradually loses her fertility, while a series of physical changes occur. Generally, the age of onset and clinical manifestations can determine whether a woman is in perimenopause. The perimenopause is a period of about 3-5 years between the beginning of the decline of ovarian function and one year after menopause, usually occurring at the age of 45-48. (2) Judgment according to clinical manifestations (1) menstruation: manifested as menstrual disorders, prolonged periods, increased menstrual volume, etc.; (2) blood vessels: mainly manifested as flushing, bouts of fever, sweating and other vasodilatory symptoms; (3) skin: collagen loss accelerates, skin wrinkles deepen, skin more fragile; (4) emotional changes: emotional instability, agitation and irritability, depression, etc.; (5) bones and joints: back pain, joint pain, prone to bone pain. (5) Bone and joint: back pain, joint pain and osteoporosis. Generally, when a woman shows the above symptoms at the age of 45-48, she can be considered to be in the perimenopause. 2, perimenopausal women’s health care methods 1, regular physical examination: recommended to focus on screening cervical cancer, breast cancer, regular bone density measurement; 2, weight management: maintain a reasonable weight, overweight people lose 5%-10% of body weight, can improve the symptoms; 3, diet regimen: low calorie, low fat, low salt, low sugar diet, avoid tobacco, alcohol, coffee, strong tea, etc.; 4, appropriate exercise: accumulate more than 6000 steps a day Physical activity: accumulate more than 6,000 steps per day, heart rate of 150 beats/min during exercise; 5, adjust the state of mind: listen to music, play and other methods to transfer negative emotions and keep a happy mood.