Patient Wang Mou, male, 32 years old, infertile for 5 years after marriage, his wife did not see any abnormality in the clinic, the patient checked his semen for many times and showed that he had severe oligozoospermia, and he had been treated with medication in many hospitals without any improvement, and then he underwent the treatment of “in vitro fertilization” in the hospital, and his wife finally gave birth to a healthy baby. Male infertility is defined as having regular sexual life for more than one year without taking any contraceptive measures, but not getting pregnant because of the male factor. The best diagnostic procedure for an infertile man is to start with a history and physical examination, followed by a semen test. A semen test is an important way to determine male fertility and is a mandatory test for male infertility. Routine semen examination can analyze sperm density, vitality, viability, sperm malformation rate, liquefaction, so as to be able to determine the existence of oligospermia, weak spermatozoa, azoospermia, semen non-liquefaction, etc., and then through the semen specifics to determine the cause of the disease and examination, which will help further treatment. Our center has the most advanced gynecological laboratory in northern Guangdong, and carries out the most complete gynecological examination programs, including: various examinations for male infertility, such as computer-assisted semen analysis, sperm morphology, MAR, HOS analysis, semen biochemical testing, sperm acrosomal enzyme assay, bacterial culture of semen and prostatic fluid plus drug sensitivity; culture of secretions of mycoplasma, chlamydia, gonococcus plus drug sensitivity; sex hormone testing; Y chromosome karyotype analysis; and Chromosome karyotype analysis; Y chromosome microdeletion detection, etc. The incidence of male infertility is increasing, in addition to the basic drug treatment, the application of assisted reproductive technology (ART) has been widely emphasized. For common male infertility such as oligozoospermia, weak spermatozoa, dyszoospermia, abnormal semen liquefaction, sexual dysfunction, genital malformation, etc., artificial insemination (AI) or in vitro fertilization-embryo transplantation (IVF-ET) can be used; for severe oligozoospermia, weak spermatozoa, dyszoospermia, irreversible obstructive azoospermia, spermatozoa dysfunction (excluding the result of genetic defective diseases), immune infertility, and spermatozoal acrosome abnormality, single-spermatozoa intracytoplasmic microprocessor injection (ICSMP) can be used. Intracytoplasmic microinjection (ICSI) treatment. Shaoguan Maternal and Child Health Hospital Reproductive Medicine Center is the only modern infertility diagnosis and treatment and assisted reproduction technology center that meets the national standard in northern Guangdong, and is the first hospital in northern Guangdong to obtain approval to carry out the “intrauterine insemination technology” after strict examination at the provincial level and the only one in northern Guangdong to legally and officially operate the IVF-EMT and its derivatives. -Embryo transfer and its derivatives (commonly known as “IVF”) technology project of the reproductive center. It represents the highest level of infertility treatment in Shaoguan City.