Staphylocytosis refers to the proliferation of placental villi trophoblast after pregnancy, with a high degree of interstitial edema and the formation of blisters of different sizes, which are connected in bunches and shaped like grapes, also known as blistered fetal mass (HM). 1. Amenorrhea: Because gravida occurs in the trophoblastic layer of the pregnant egg, there is mostly amenorrhea for 2-3 months or longer. 2. Vaginal bleeding: This is a serious symptom of spontaneous abortion of gravida. The bleeding occurs as early as around 6 weeks of pregnancy and as late as 12 weeks of pregnancy. It is intermittent small amount of bleeding, but there can be repeated heavy bleeding in between. If examined carefully, sometimes blister-like material can be found in the bleeding. The uterus is abnormally large and soft: due to chorionic edema and blood accumulation in the uterine cavity, the uterus of most patients with staphyloma is larger and softer than the uterus of normal pregnancy in the corresponding month. 1/3 of the patients have a uterus whose size corresponds to the month of menopause. The majority of the patients have a uterus larger than the normal month of pregnancy and softer. 1/3 of the patients have a uterus that matches the month of menopause. 4. abdominal pain: distension and pain due to rapid enlargement of the uterus, or pain due to contraction of the uterus stimulated by intrauterine bleeding, which can be mild or severe. 5. Pregnancy vomiting and hyperemesis: Since the proliferating trophoblast cells produce a large amount of HCG, vomiting is often heavier than normal pregnancy. In addition, because of the rapid increase in uterine size and tension in the uterus, gestational hypertension syndrome can occur in the middle and early stages of pregnancy, and even acute heart failure or eclampsia. 6. No fetus: no fetal sac, fetal heart and fetus are found in ultrasound monitoring around 8 weeks of amenorrhea, and even at 18 weeks, no fetal movement is felt and no fetal heart can be heard, and ultrasound scan shows snowflake-like images without fetal images. 7. Ovarian flavinized cysts: Due to the stimulation of large amount of HCG, patients with gravida often have multiple cystic changes in one or both ovaries. They are usually asymptomatic and occasionally have acute abdominal pain due to acute torsion. The flavin cysts may resolve on their own after clearance of the gravida. The cysts can store a large amount of HCG, so patients with huge cysts after the gravida is expelled will have slower disappearance of blood and urine HCG than normal patients. 8. Hemoptysis: some patients may have hemoptysis or sputum with blood. 9. Anemia and infection: repeated bleeding without timely treatment will definitely lead to anemia and its related symptoms, and individual may even die due to bleeding. Repeated bleeding can easily lead to infections, such as unclean vaginal operations or sexual intercourse during bleeding, which can easily lead to infections. Infection can be confined to the uterus and adnexa and can lead to sepsis. 10, hyperthyroidism phenomenon: a few patients with hyperthyroidism appear mild hyperthyroidism, plasma thyroxine concentration increases, but only about 2% appear obvious signs of hyperthyroidism, the symptoms disappear quickly after the clearance of the gravida. In short, as long as these symptoms appear, we should pay attention to them and go to the hospital in time for examination, after treatment will not affect future fertility