In the first month of glucose, the clinical manifestation is often early reaction to early pregnancy, with nausea and vomiting appearing earlier than in other pregnant women, mainly caused by the abnormal increase of HCG in the body due to glucose. As the glucose continues to increase in size, it will show irregular vaginal bleeding, abnormal enlargement of the uterus and abnormally high blood HCG, even up to 100,000 units or more. Once glucose is detected clinically, it is important to give clearance surgery as soon as possible and send the cleared tissues for pathological examination to understand whether there is a possibility of malignant grapes. After 1 week of clearance, a second clearance is done and the cleared tissue is also sent for pathological examination and the change of blood HCG is closely monitored after the procedure.