Step 1: Outpatient visit to confirm the need for artificial insemination by husband (AIH)
I. Who are suitable for AIH
1.Male infertility due to oligospermia, weak sperm, liquefaction abnormality, sexual dysfunction, genital malformation, etc.
2, female infertility due to abnormal cervical mucus secretion, genital tract malformation and psychological factors leading to inability to have sexual intercourse, etc. Tan Zongjian, Reproductive Center of Guizhou Provincial People’s Hospital
3, immune infertility.
4, infertility of unknown cause.
II. Who are not suitable for AIH
1.The female partner has obstacle in combining sperm and egg due to tubal factors.
2. The female partner suffers from acute infection of the genitourinary system or sexually transmitted diseases.
3.The female partner suffers from genetic diseases, serious physical diseases, mental and psychological disorders.
4.History of birth of babies with congenital defects and confirmed to be due to female factor.
5.The female partner is exposed to teratogenic amount of radiation, poison, drugs and is in the period of action.
6.The female partner has alcoholism, drug addiction and other bad habits.
Step 2: Outpatient consultation and AIH preparation by the attending doctor
I. Examination before AIH
(I) Female partner
1.Blood hormone.
2. hysterosalpingogram.
3.Blood routine.
4. urine routine.
5.White belt routine.
6, Torch.
7, Infertility antibodies.
8.Blood group.
9. Infectious diseases, cervical mycoplasma and chlamydia.
(II) Male partner
1, Semen routine + ASAb.
2.Blood group, infectious diseases.
3.Other necessary tests
Second, the couple needs to prepare the materials
ID card of both parties, marriage certificate, valid birth certificate (such as birth certificate).
Caution: If abnormalities are found in the above tests, treatment is required before AIH pregnancy assistance can be performed. The examination for infectious diseases is generally valid for 6 months, and will be re-examined after that time. If the male partner has oligozoospermia, at least one re-examination is required.
Step 3: Visit the hospital and arrange for AIH fertility treatment
I. Sign the treatment information document
Before the treatment, both partners must bring one original and one copy to the hospital to sign the consent form and other documents, and the doctor will also inform you about the precautions and treatment plan.
II. Preparation of ovulation cycle plan
1. Natural cycle. It is suitable for patients who have regular menstruation and normal ovulation. The doctor will make a follow-up appointment according to the follicle development until the follicles are mature.
2. Ovulation promotion cycle. It is usually started on the 5th day of menstruation and may be delayed in some patients with many sinus follicles. Some patients may use imported follicle stimulating hormone, and a few patients may use a down regulation regimen, which will be arranged on a case-by-case basis.
Precautions
1. In natural cycles, some patients may use ovulation-promoting drugs or cancel them due to follicular dysplasia.
2. During ovulation promotion cycle, some patients may experience ovarian hyperstimulation and the cycle will be cancelled if the number of mature follicles is greater than 3. Some patients may experience poor ovarian response and the cycle will be cancelled.
3. When follicle monitoring starts in the natural cycle or when medication is started in the ovulation promotion cycle, a treatment fee is required. This fee will not be refunded if the cycle is cancelled.
4. At the time of follicle diameter up to 14mm, the male partner will ovulate 1 time.
Step 4: Hospital visit to induce ovulation
1. Natural cycle. Generally, no medication is used to induce ovulation. After the follicle diameter reaches 14mm, daily hospital visits are required for ultrasound monitoring, urine LH testing and, if necessary, blood LH, E2 and P checks until urine LH is positive.
2. Ovulation promotion cycle. After the follicle diameter reaches 14mm, you need to go to the hospital every day for ultrasound monitoring, urine LH test, and blood LH, E2, P if necessary. when the follicle diameter reaches 18mm and the urine LH is negative, HCG injection will be given to induce ovulation.
Step 5: Hospital visit and artificial insemination
1. Sperm retrieval by the male partner. The patient couple should go to the hospital according to the doctor’s appointment time. The male partner should bring his ID card and original marriage certificate, and then masturbate for sperm retrieval after the doctor’s verification.
2.Artificial insemination. The doctor will finish processing the male partner’s semen in the laboratory, and the female partner will enter the operation room for artificial insemination according to the hospital’s requirements. The operation can generally be completed in 10 minutes, and the patient will rest in bed for 30 minutes in the observation room after the operation.
Step 6: Fertility center visit and review
Patients will be monitored for ovulation by ultrasound at the hospital at the time of the doctor’s appointment. If ovulation occurs, some patients will be given luteal support treatment. A small number of patients may have non-ovulatory luteinization, then this cycle is ineffective in assisting pregnancy. Go to the hospital for blood HCG test 17 days after IUI, if positive, go to the hospital ultrasound after 31 days to find out the status of the pregnancy sac, if negative, stop the luteinizing support medication and wait for the menstruation.