In our daily practice, we encounter a variety of patients with mood disorders. In fact, they come to clinicians not to confide in psychological confusion and relieve psychological stress, but to help solve various physical discomforts. Various clinical departments in general hospitals may accept these patients, especially cardiovascular, gastroenterology, neurology, Chinese medicine, gynecology, emergency medicine, etc. What is a mood disorder? Simply put, emotion is the intensity of a person’s reaction to changes in the environment. Emotion is a product of human evolution and is closely related to the natural social environment in which people live. Human emotions are very complex, but they are composed of four basic emotions: happiness, sadness, anger, and fear. In addition to happiness, sadness, anger, and fear are all negative emotions, or called bad emotions. With the transformation and change of society, people are under more and more pressure, and there are more and more opportunities for negative emotions to dominate. If a person is in the grip of bad emotions for a long time, and can not change with the passage of time and environmental changes, and lose the ability to self-regulate, then it is the occurrence of emotional disorders. Continuous psychological stress or tension, sudden event strikes are the main factors that contribute to negative mood disorders. Why are there especially many patients with mood disorders in general hospitals? According to statistics, more than 95% of patients with mood disorders go to general hospitals for help, and more than 20-30% of patients in general hospitals have different degrees of mood disorders, of which there are reasons for both doctors and patients: from the patients, feel physically unwell, of course, go to the doctor, many patients with mood disorders have a variety of physical discomfort, such as dizziness, panic, shortness of breath, breath-holding, chest and back pain, extremities Numbness, sweating, bloating, nausea, indigestion, urinary frequency and urgency, etc., a wide range of complaints, involving various organs and systems, as well as severe fatigue, a sense of weakness, tinnitus, insomnia, a variety of strange feelings, etc., seems to be uncomfortable from head to toe, this is called mood disorders “somatization” phenomenon, such as a momentary difficulty in the diagnosis, more will aggravate the patient’s doubts From the doctor’s point of view, the lack of understanding, too detailed subspecialty, used to start from the organ disease, see “sick organs” but not “sick people”, ignore the patient’s psychological and emotional problems, resulting in many patients with mood disorders seem to become a difficult and complicated disease. What kind of mood disorder patients need treatment? Treatment depends on the severity and persistence of the mood disorder, if it affects the patient’s normal work life and study, brings confusion and pain to the patient, and cannot get rid of itself, then it needs to be treated. More and more clinical evidence confirms that mood disorders also have a direct role in promoting the occurrence of certain diseases, such as hypertension, heart attack, arrhythmia and sudden death, cancer, diabetes, etc., and affect the recovery of the disease, the patient for a long time to move around the hospital bed, seeking medical treatment, to the family and society brought a huge economic and mental burden, and even lose the courage to live, leading to suicide or murder, such as the Wenling murder case, resulting in a human tragedy. The harm is not to be underestimated! How to treat mood disorders? In mild cases, the main treatment is psychological guidance, expressing care, giving sympathy, listening well, and patiently solving problems, which is not only the method of psychological treatment, but also the psychological quality that doctors should have. More serious patients medication is very necessary, in recent years the use of SSRI class anti-anxiety depression drugs with exact efficacy, such as sertraline, Celerity, Baiyao Xie, Lysop, venlafaxine, etc., Chinese medicine, Wu Ling capsule as China’s independent development of a new class of drugs, for mild to moderate mood disorder patients have good therapeutic effect, long-term use of almost no side effects, so it is also gaining attention.