Sodium bicarbonate has a role in the treatment of gout, but it needs to be used under the guidance of a rheumatologist. The current treatment of gout is based on the principles of rapid relief of joint swelling and pain in the acute phase and reduction of uric acid level in the intermittent and remission phases, with the aim of reducing the frequency of acute gout attacks, preventing the formation of uric acid stones and reducing organ damage. Commonly used drugs include non-steroidal anti-inflammatory analgesics, colchicine, glucocorticoids, uric acid production inhibitors and uric acid excretory drugs. Sodium bicarbonate cannot eliminate the joint inflammation caused by gout, nor can it directly reduce uric acid levels. In gout treatment, sodium bicarbonate has the effect of alkalinizing urine. Current research has found that the pH value of urine in gout patients is acidic, about 5.0 to 6.0, which is not conducive to uric acid excretion. After alkalinizing urine by sodium bicarbonate and improving urine pH, it can improve the efficiency of urine excretion of uric acid and promote uric acid excretion, thus reducing blood uric acid level. For gout patients with acidic urine PH, sodium bicarbonate does have a certain therapeutic effect, but for gout patients, the higher the urine PH, the better. This is because there is a risk of inducing urinary stones if the urine PH level is too high. Therefore, for gout patients, the use of sodium bicarbonate has a certain therapeutic effect on gout, but it must be done under the guidance of a rheumatologist, as well as regular review of urine routine to check the PH value.