Sodium bicarbonate tablets are an alkaline drug that can lower uric acid and cure gout by alkalizing the urine so that uric acid is less likely to accumulate in the urine. If sodium bicarbonate tablets are taken according to medical advice, there are usually no obvious side effects in the short term; however, if taken in large quantities for a long time, gastrointestinal symptoms, such as gas and bloating, may occur. In severe cases, it may cause metabolic alkalosis, sodium overload, and other side effects. Therefore, do not take this drug on your own, but under the guidance of a doctor: 1. Gastrointestinal symptoms: sodium bicarbonate tablets can produce a large amount of carbon dioxide after reacting with gastric acid in the stomach. Under long-term use, it can cause symptoms of gas, burping, thirst, and even stomach cramps; 2. Metabolic alkalosis: sodium bicarbonate tablets, when taken in large quantities for a long time, can cause too much bicarbonate in the body, causing disorders in the acid-base balance of the body, resulting in metabolic alkalosis. Further development can cause a series of side effects such as irritability, twitching of limbs, numbness of limbs, cardiac arrhythmia, etc.; 3. Excessive sodium load: sodium bicarbonate tablets, when taken in large quantities for a long time, can cause excessive sodium load in the human body. As sodium cannot be eliminated normally for a long time and then stays in the body, it may cause water and sodium retention, leading to side effects such as edema in the body.