For diabetic ketoacidosis, a small-dose insulin regimen is usually used, with intravenous infusion and simultaneous rehydration therapy with saline, and subcutaneous insulin can be used instead after blood glucose is restored and the condition is stabilized. Diabetic ketoacidosis is a syndrome in which diabetic patients suffer from severe insulin deficiency under the effect of various triggers, leading to imbalance of sugar, protein, fat, water, electrolyte and acid-base, thus causing hyperglycemia, ketonuria, dehydration, electrolyte disorders, metabolic acidosis and other manifestations. Acute phase treatment should be given intravenously with small doses of insulin, which can lower blood glucose and inhibit ketone body production. At the same time with saline rehydration therapy, blood glucose recovery and stabilization of the condition can be changed to subcutaneous injection. During insulin treatment, patients’ blood glucose, blood potassium, urine output and other indicators must be closely monitored. Diabetic ketoacidosis should be timely consultation, under the guidance of the doctor for formal and effective treatment.