When we talk about chemotherapy, we have to mention its side effects. The first impression that many people have of chemotherapy is severe hair loss, vomiting, etc. However, the chemotherapy regimen used to treat hard fibroids is a low-dose chemotherapy and has relatively few side effects. So, what are the side effects associated with the use of chemotherapy for patients with hard fibroids? How to deal with these side effects? The most common side effects of chemotherapy are liver function injury, which is mainly manifested as elevated glutathione transaminase and glutamic oxalacetic transaminase when blood is drawn and tested. These transaminase elevations usually occur at the beginning of chemotherapy, and the doctor will adjust the chemotherapy dose and the dose of liver-protective drugs according to the transaminase elevation. When the aminotransferase level rises to about 80 U/L, the doctor will recommend that the patient suspend chemotherapy or increase the dosage of liver-protective drugs until the aminotransferase level drops to normal. For the specific treatment of elevated transaminases, it is recommended to consult the attending physician; 2. Oral ulcers: Oral ulcers are also very common in patients with sclerofibrosarcoma undergoing chemotherapy. When oral ulcers appear, if the symptoms are not serious, they can be treated without treatment; if the symptoms are severe, it is recommended that ulcer patches and ulcer dispersion can be used. In addition, 3mg of calcium folinic acid injected into 250ml of saline and rinsed directly into the mouth is also effective in treating mouth ulcers; 3. Nausea and vomiting: Generally speaking, nausea and vomiting will only occur in the initial stage of chemotherapy for hard fibroids, and these symptoms are rare and mild; 4. And this small dose of chemotherapy for bone marrow suppression is relatively low, patients do not need to worry excessively about pediatric patients after chemotherapy will lead to leukemia. The most common manifestation of myelosuppression is a decrease in white blood cells when blood is drawn for laboratory tests. During chemotherapy for sclerofibrosarcoma, the degree of leukocyte reduction is limited, and unless the leukocyte reduction is very severe, there is usually no need for leuke-raising injections. Does chemotherapy affect the growth and development of the child? Because chemotherapy for sclerofibrosarcoma is a low-dose chemotherapy, the side effects are reversible and do not have a serious impact on growth and development. Moreover, the methotrexate used in the chemotherapy regimen, which is commonly used for children with leukemia, is used in much larger doses for the treatment of leukemia than for sclerofibrosarcoma, and these children with leukemia have not experienced abnormal growth and development after treatment. Also, because chemotherapy involves the use of hormones, many parents worry about the side effects of hormones, which is also unnecessary. The purpose of using hormones in chemotherapy for hard fibroids is twofold: one is to prevent drug allergy; the other is to stop vomiting. If the patient does not have any side effects after 1-2 times of hormone use at the beginning of chemotherapy, the hormone can basically be stopped in the subsequent chemotherapy. In other words, chemotherapy for hard fibroids is not a long-term use of hormones; therefore, there is no need to worry excessively about side effects. Besides, some patients reported swelling and pain in the tumor growth area during chemotherapy, is there any problem with chemotherapy? In fact, the pain and swelling sensation just indicates that the tumor is responding to chemotherapy, that is, chemotherapy is working. Because during chemotherapy, the tumor will swell up and then start to necrotize and shrink. Therefore, these sensations are very normal during chemotherapy, and if patients are still worried, it is recommended to consult the attending doctor.