Selection of Hepatitis B Tests Recently, we often encounter parents requesting Hepatitis B tests in the clinic, mostly for kindergarten screening, or for Hepatitis B vaccination, and a few have relatives with Hepatitis B for screening purposes. In this case, we will ask about the child’s medical history and the purpose of the test, and suggest to the family that they should undergo the past hepatitis B test (qualitative test) or quantitative monitoring of the hepatitis B triplet. However, it is still difficult to explain clearly within a short time of the visit, so I would like to explain it here for the parents and friends to facilitate the family’s choice. Liver disease experts said that the hepatitis B two-to-one half has a total of five indicators: hepatitis B surface antigen (HBsAg), hepatitis B surface antibody (anti-HBs), hepatitis B e antigen (HBeAg), hepatitis B e antibody (anti-HBe) and hepatitis B core antibody (anti-HBc), each of which represents a different meaning, and different combinations represent different conditions. 1, before the downtown hospital can only carry out enzyme immunoassay to check the five hepatitis B, that is, qualitative examination, the cost is low only 25 yuan. But because the hepatitis B virus is prone to mutation, coupled with the limitations of the hepatitis B qualitative test method, there will be false-negative results, resulting in the failure to detect hepatitis B infection in a timely manner, and will not be able to get timely treatment. The result of this test is also not accurate if only the hepatitis B surface antibody (anti-HBs) is positive, whether it must have the ability to protect. It is suitable for general screening of healthy people. 2, now in order to improve the accuracy of the test, our hospital has introduced the chemiluminescence method to detect hepatitis B five, that is, quantitative examination, but the cost is higher, each for 44 yuan, a total of five 220 yuan, can be a single item for examination. Hepatitis B five quantitative tests apply the most advanced chemiluminescence method currently available to detect the concentration of each marker, avoiding the problems of false negatives and missed tests, and are accurate. It especially provides a basis for the observation of the efficacy of hepatitis B patients. 3, quantitative check analysis can make a correct evaluation of whether the antibody really has the immunity to neutralize the hepatitis B virus, and play a supervisory role in the prevention of hepatitis B. (1) The level of hepatitis B surface antibody (anti-HBs) is in the range of 0~10mIU/ml, indicating that it is not protective and requires hepatitis B vaccination (3 shots: 0-1-6 program). (2) The content of anti-HBs is between 10~100mIU/ml, which means it is protective but weak and needs hepatitis B vaccination booster (1 dose), such situation can show positive result of HBsAb in the previous qualitative test, but it cannot reflect the strength of immunity. (3) The content of anti-HBs is greater than between 100mIU/ml, indicating strong protection and no need for hepatitis B vaccination. (4) Whether the qualitative and quantitative tests suggest a major or minor hepatitis B triplet, they do not represent the condition of the disease. Further tests such as liver function, hepatitis B virus variant resistance testing, viral DNA, liver ultrasound, etc. are needed to comprehensively analyze the condition. 5, for healthy people, the hepatitis B vaccine can produce a sufficient amount of hepatitis B antibodies, 3-5 years to check the hepatitis B five can, in addition, for people who are often in contact with hepatitis B patients, it is best to check the hepatitis B antibody titer (quantitative) every year, once the titer is less than 10, should be timely vaccination hepatitis B vaccine booster shot. For hepatitis B patients, the interval between hepatitis B tests should be based on their own situation, neither should the interval be too long, but it is also meaningless to check too frequently. In general, patients are advised to have their hepatitis B tests every three months or six months. The hepatitis B test is often performed together with the liver function, especially for hepatitis B patients who are already showing symptoms of hepatitis B. If you feel that your condition is a bit abnormal, go to the hospital for a checkup.