Whether or not whiteheads disappear on their own is determined by the specific condition and the individual patient, and cannot be generalized. Whiteheads are a type of acne, also known as closed acne, and are actually sebum plugs that accumulate under the epidermis. If the number is small, patients can improve their whiteheads by adjusting their daily routine, improving bad habits, such as eating less spicy and oily food, and improving their immune function, which can lead to a certain improvement of whiteheads or to their disappearance on their own. However, if the number of whiteheads is relatively large and dense, they usually cannot recover on their own. Patients should actively take oral or topical medication under the guidance of a doctor to regulate keratin metabolism, thus promoting the smooth opening of the sebaceous glands of hair follicles and the smooth discharge of sebaceous plugs, so that whiteheads disappear. In addition, during the treatment period, it is important to follow the doctor’s instructions to regulate the application of medication to avoid overuse of medication, which may cause skin irritation, redness, swelling, stinging and other adverse reactions.