Some leukemias can be completely cured, while others have poor outcomes even with a bone marrow transplant. Leukemia is divided into acute myeloid leukemia, acute lymphocytic leukemia, chronic myeloid leukemia, chronic lymphocytic leukemia, and other rare types of leukemia, such as hairy cell leukemia and eosinophilic leukemia, which can be treated differently depending on the leukemia classification. Chronic myeloid leukemia used to be an incurable disease, but now, with targeted therapies, patients can get long-term remission after taking oral medications, and it is now a curable disease. One type of acute myeloid leukemia is acute promyelocytic leukemia, which used to be a severe critical, acute bleeding leukemia with a mortality rate of more than 90%. After the discovery of targeted therapeutic drugs arsenic and retinoic acid, acute promyelocytic leukemia is now also a curable disease. There are also specific acute myeloid leukemias, such as acute myeloid leukemia of M4EO, which, after standardized chemotherapy, can result in long-term survival of about 60% or more of patients for five years, and clinically, five-year long-term survival is considered a cure, but some patients may relapse.