Concept: Meibomian Gland Dysfunction (MGD) refers to all disorders of the lid gland that result in abnormal lid gland function. It is characterized by abnormalities in the nature (quality and quantity) of the lid gland secretions. MGD is the main cause of lipid deficiency dry eye (excessive tear evaporation) and can also cause blepharitis, conjunctivitis, punctate keratitis, and other ocular surface diseases. Zhang Hongwen, Ophthalmology Department, Jixian People’s Hospital, Tianjin, China Clinical manifestations: non-specific, mainly including eye redness, burning sensation in the eye, foreign body sensation, dryness, irritation, itching, visual fatigue, fluctuating vision and tearing. Clinical examination: lid margins are congested, irregular, thickened or bluntly rounded, capillaries around the glandular openings are dilated, and the lid gland openings are displaced by projection, atresia, poorly defined, reduced in number, and often obstructed by a solid yellow discharge. Other manifestations include conjunctival congestion, papillary hyperplasia, punctate staining of the cornea, chalazia and conjunctival calculi, and in more severe cases, corneal vascular opacification and corneal ulceration with ectropion. Eyelid massage test: Normal lid gland secretions are a colorless, clear fluid. In obstructive and hypersecreting patients, there is often no discharge; in hypersecreting patients, a large amount of cloudy, foamy, granular, or toothpaste-like lid secretions may be pressed out. The diagnosis of MGD is difficult to make using a single criterion because of the lack of uniformity in the classification, but the diagnosis can be made as long as the examination reveals glandular defects, abnormalities in the lid margin and lid opening, and changes in the quantity and quality of lid secretions. shampoo to clean the lid margin and eyelashes.1.2 Hot compresses on the eyelids and massage of the lid glands: hot compresses are used to promote the flow of lipids by raising the temperature above their solubility point and then squeezing out the gland contents by massage.1.3 Topical antibiotic and hormonal eye drops: for those with staphylococcal infections, and corticosteroid eye drops only for those with significant inflammatory manifestations, but only for short-term applications to avoid adverse reactions.1.4 Artificial tears and lipid-based eye drops: Patients with MGD often present with significant conjunctival dryness, and the use of ocular lubricants to spot the eyes is effective in relieving symptoms.2. Systemic therapy: Systemic therapy is used only in patients with more pronounced symptoms and on top of local therapy.2.1 Those with significant inflammation: This includes oral tetracycline or doxycycline, which are lipophilic antibiotics that reduce bacterial lipase products, such as fatty acids, and thus achieve therapeutic control of blepharitis. 2.2 Red acne and seborrheic dermatitis: A dermatologist should be consulted for appropriate treatment. 2.3 Screen end-users at work: The screen should be placed in a lower position, with a smaller exposed area of the eye surface when gazing downward, so that less tear fluid evaporates and the tear film disintegration time is correspondingly prolonged, relieving dry eye symptoms. 2.4 Androgen application: can improve the secretion function of the lid gland. 2.5 Traditional Chinese medicine and food therapy: eat less fishy, stinky, spicy, stimulating food, less hot food, such as dog meat, deer blood meat, etc., while not drinking alcohol. And you can eat some slow drainage agents, heat-clearing Chinese medicine.