Portaline aminotransferase, or glutamate aminotransferase, is found mainly in the heart muscle, liver, skeletal muscle, kidney and other tissues. Most patients with no other pathological symptoms only have high serum ghrelin concentration, which is usually caused by prolonged late night, poor sleep, excessive alcohol consumption and excessive exercise. In addition, it can also be seen in liver and gallbladder diseases, heart diseases, etc. 1. Liver and gallbladder diseases: Patients with high serum ghrelin activity may also be associated with liver diseases such as hepatitis, cirrhosis, liver stasis, liver cancer, and biliary tract diseases such as cholecystitis, gallstones, biliary tract infections, and biliary tract tumors. If patients have significantly higher glutamic oxalyl aminotransferase along with significantly higher glutamic alanine aminotransferase, it usually indicates acute viral hepatitis, etc.; 2, heart disease: if patients suffer from myocardial infarction, myocarditis and other heart diseases can also lead to high glutamic oxalyl aminotransferase, and the specific degree of increase is usually proportional to the size of the infarct lesion; 3, other: muscle injury and other diseases can lead to high glutamic oxalyl aminotransferase transient. It is not possible to make a clear diagnosis of the patient by only one test result of high glutamic transaminase, so it is recommended that the patient should go to the hospital in time to clarify the cause and actively carry out targeted treatment to avoid aggravation of the disease.