First, depression treatment should not be pregnant during Miss Chen, 23 years old, six months after marriage often insomnia, anorexia, lost a lot of weight, all day lethargy, not interested in anything, often alone in tears, feel sorry for her husband. The doctor diagnosed her with depression and gave her antidepressants Amitriptyline and GlaxoSmithKline for treatment, which improved after about 1 month, and continued to take Amitriptyline for consolidation. About 4 months later she told her doctor that she was 2 months pregnant. She was worried: Does amitriptyline have any effect on the fetus? Is it possible to stop taking the medication? Depression is a mental illness and it is obviously not advisable to get pregnant during treatment. Since any type of antidepressant passes quickly through the placenta, it may have an effect on the fetus. In the United States, no antidepressant drug has been approved by the FDA for use in pregnant women. The FDA classifies drugs into five categories, A, B, C, D, and X, based on clinical and animal test data. Category A is the safest to use in pregnant women, and Category X is prohibited in pregnant women because these drugs are definitely harmful to the fetus. The vast majority of antidepressants commonly used in clinical practice today are class C. In addition to this, toxic reactions or withdrawal syndromes occur in the postpartum period, which are relatively common side effects, such as intestinal obstruction, sensitivity, irritability and seizures in newborns of those taking tricyclic antidepressants during pregnancy. Newborns taking newer antidepressants during pregnancy can have adjustment difficulties, breathing difficulties, feeding difficulties, and irritability, but most are not serious and usually resolve within a short period of time. Some patients and even doctors, worried about the effect of antidepressants on the fetus, stop taking antidepressants during pregnancy and use only Valium as an alternative treatment, thinking that Valium has fewer side effects and is safer for the fetus. In fact, this alternative treatment plan is even more undesirable, because most Valium drugs belong to class D or X, which have a greater impact on the fetus than antidepressants. Second, pregnant women need to be more careful with medication for depression. During pregnancy, you should try not to take medication, but if a pregnant woman suffers from depression can still be treated? The latest research data shows that the prevalence of depression among women of childbearing age 25-44 is 10%-20%, and the risk of depression is equal for pregnant and non-pregnant women; on the other hand, women with a previous history of depression have an increased risk of depression after pregnancy, especially in the first trimester. Pregnant women should be more cautious in antidepressant treatment during pregnancy and try to use medication that has little effect on the fetus. Third, depression in pregnant women should be treated actively People pay more attention to the effects of antidepressants on the fetus, but ignore pregnant women. Pregnant women will do a lot of dangerous behaviors after the disease, which is a kind of harm to pregnant women; bad mood of pregnant women during pregnancy will also have a negative impact on the fetus, so depression in pregnant women should be treated actively.