When pleural effusion occurs in pulmonary tuberculosis, the time of cure varies according to the conditions causing the pleural effusion, such as secondary pulmonary tuberculosis, tuberculous pleurisy, interruption of anti-tuberculosis treatment, etc. It may be about 6 months, or it may be more than 6 months, or even longer. 1. Secondary tuberculosis: If the pleural effusion is caused by secondary tuberculosis, anti-tuberculosis drugs need to be applied, such as isoniazid and rifampicin, etc., and it can be cured in about 6 months. However, once TB develops drug resistance, the treatment time may exceed 6 months or even longer. 2. Tuberculous pleurisy: If tuberculous pleurisy causes pleural effusion, it is easy to recur, and usually it may take more than one year to be cured after active anti-tuberculous treatment and fluid extraction. 3. Treatment interruption or relapse: If there is treatment interruption or relapse in the course of anti-tuberculosis treatment, causing pleural effusion, the treatment time will be prolonged, which may be about 6-12 months or longer. Therefore, when pleural effusion occurs in pulmonary tuberculosis, it is recommended to cooperate with professional tuberculosis doctors to carry out standardized anti-tuberculosis treatment as soon as possible, and actively control the condition to avoid serious development of the disease.