TCT reactive cell changes may be caused by vaginitis, cervicitis, cervical precancerous lesions. It is necessary to clarify the cause and give reasonable treatment and treatment as follows: 1. Vaginitis: TCT test reactive cell changes indicate the presence of inflammatory cells in the cervix, which can be combined with the results of leukostatic tests to see if vaginitis exists at the same time. Vaginitis is mainly treated by oral or local vaginal medication, commonly used drugs are metronidazole or tinidazole, which should be used in sufficient quantity and duration to avoid incomplete treatment or recurrence. It may be accompanied by increased vaginal discharge or abnormal bleeding. The main application of local medication, antibiotic anti-infection treatment if necessary, daily life should pay attention to sexual safety, fixed sexual partners, good hygiene habits, pay attention to private cleanliness and dryness; 3, cervical precancerous lesions: TCT reactive cell change does not exclude that it is caused by cervical precancerous lesions, it is recommended that women further improve colposcopy or biopsy pathology to exclude malignant lesions. Cervical precancerous lesions have the potential to develop into malignant tumors and may turn into cervical cancer in the long term, which can last from several years to several decades. It is recommended to raise the awareness of prevention, avoid premature sex, eliminate sexual confusion, and have regular cervical cancer screening for early detection and treatment.