How can antipsychotics be safely applied during pregnancy?

As we all know, the high incidence of schizophrenia coincides with the childbearing age, the face of these patients will inevitably need to consider the patient’s reproductive problems, unfortunately, even though the doctor mentioned the issue of reproductive risk, but there are still many patients who do not listen to advice or accidental pregnancy in the clinic. First, which pregnant women need to use antipsychotic drugs? 1.Women who are taking antipsychotic drugs and plan to have children in the near future. 2.Women who are taking antipsychotic drugs and are pregnant. 3.Women who develop mental disorders during pregnancy and need to use antipsychotic drugs after assessing their risks and benefits. Whether to use or not to use, is a very tangled thing, use, will expose the fetus to risk, resulting in fetal extrapyramidal reactions and malformations and other adverse reactions; but not to use, perhaps resulting in higher risk of mother and child. Overall, for pregnant women with schizophrenia, the benefits of taking medication outweigh the risks of not taking it. Second, what should I pay attention to when using antipsychotics during pregnancy? 1, the first trimester of pregnancy, it is best not to use antipsychotic drugs (please take into account the actual situation), in the second trimester of pregnancy, should also be used when necessary. 2.Patients who need to take antipsychotic drugs during pregnancy can choose relatively safer drugs with the lowest dose that can control the patient’s condition. 3, need to take into account the pregnancy throughout the patient’s weight, metabolism, excretion and other changes, the dose needs to be adjusted accordingly. Avoid the use of long-acting antipsychotic drugs, avoid joint use of drugs, and avoid the use of diuretics. 5.Routine monitoring of urine sugar and body weight. 6.Strengthen the blood concentration and fetal testing during drug administration, and supplement folic acid and vitamin K to reduce the risk of neural tube malformation. Third, what do I need to pay attention to after giving birth? 1, pregnant women after giving birth, the body estrogen will plummet, because of its antagonistic dopamine effect, in the postpartum level will cause a rebound increase in dopamine after the plummet, may make the relapse rate of schizophrenia suddenly rise. 2, because of the high risk of relapse in the postpartum period, patients who have stopped taking medication need to restart medication, and if the mother was taking clozapine during pregnancy, she needs to review the neutrophils of the newborn and preferably avoid breastfeeding. 3.Because of the birth and antipsychotic drugs, mothers taking antipsychotic drugs are more likely to be obese, so they need to pay attention to weight management.