Many patients’ questions in writing, or on the phone, are often about these elements, which are actually answered in my article. I will repeat here: 1, the application of antipsychotics, whether it is risperidone, or olanzapine, will inevitably appear extrapyramidal side effects. But after all, the family is not a psychiatrist, once the side effects, also do not recognize, but also thought out of the big problem, nervous, do not know what to do. So I suggest you, in order to avoid this situation, it is better to take Benzhexol in advance, 2 times a day, each time 1 to 2 tablets. Don’t listen to those calumnies, saying that ‘Benzhexol affects liver function and memory’, and so you don’t dare to take Benzhexol even if you are suffering from a lot of pain. In fact, those are nonsense, do not believe it. 2, generally speaking, Benzhexol eliminates the side effects of meditation inability, not ideal. It is more effective to take Xanax at the time of inability to sit still. The usual dosage is 1 to 2 tablets each time. The symptoms of inability to sit still can be various, such as restlessness, fidgeting, feeling itchy inside the body (or inside the bones), and so on. 3, antipsychotic side effects, such as drowsiness, extrapyramidal side effects, inability to sit still, increased appetite, and so on, often occur on the same day or one or two days after taking the drug, immediately. However, their therapeutic effects are not apparent until more than 1 week (generally speaking, 2-4 weeks). Therefore, every time you increase the variety of medication, or change the dosage, it is necessary to observe for 2-4 weeks. Any immediate changes in the condition, whether good or bad, are often fluctuations in the condition itself, with no direct relationship to the drug. 4, schizophrenia patients, after the application of antipsychotic drugs, the condition will often appear different degrees of improvement. But this does not mean that the disease is well completely. What we ask for is not ‘basic improvement’ of symptoms, but ‘complete disappearance’ of symptoms. Only after a few months of consolidation, gradually reduce the drug to the maintenance amount (such as olanzapine 5 mg, risperidone 1 mg, etc.), and still can maintain normal, then we can say that ‘the treatment is more complete’. At this point, it is possible to switch to pentafluridol for maintenance. Otherwise, Pentafluridine will not be able to take over. 5. After the main symptoms of schizophrenia are relieved by the application of the ‘new generation’ of antipsychotics, the child often appears to be “childish, ‘clingy’ (following the parents), inattentive, and not good at thinking, Memory seems to be worse, even touching the parent’s private parts” and so on. All of these are the result of the drug inhibiting the 5NE receptor, so that the ability of self-control is weakened, and they are not the symptoms of schizophrenia itself. The situation will improve when the medication is reduced or even stopped. Drugs such as haloperidol and pentafluridol, which affect the 5NE less, are less of a problem. Of course, if the problem is more severe, you can take some Reboxetine and it may be able to improve. The dose of Reboxetine is 1 tablet twice a day (to 2 tablets each time), exactly how much varies from person to person and must be worked out for yourself. Reboxetine is not a treatment, but a supplement of 5NE neurotransmitters, so it should not be stopped. If you stop, the situation will recur. 6, no matter which kind of antipsychotics, for menstruation will be more or less some effect, only the degree of influence is different. Risperidone, Sulpiride, and Amisulpride are the ones that have a greater impact. If the medication is only taken for a few months to a year or two and the change in menstruation is not severe, then it doesn’t matter. If one is on medications such as risperidone for life, or if they have a significant effect on menstruation, then it is worth considering. The rest of the antipsychotics, which have less or little effect on menstruation, are not a problem. If the medication affects menstruation, don’t use medication such as progesterone, that just creates some fake menstruation for you, which is really just artificial ‘vaginal bleeding’. However, progesterone inhibits the endocrine ‘command’ pituitary gland, so that the command that has been inhibited, into a ‘strike’ state, the result is more pushed back the adjustment of menstruation. 7. There is no relationship between pregnancy and taking or not taking antipsychotics. As long as there is still normal menstruation and normal ovulation, pregnancy is possible. As for the effect of antipsychotics (maintenance dose) on the fetus, it is completely negligible. Some drugs are fat soluble, so the level in breast milk is higher, and you can consider not breastfeeding “as much as possible”. If you really want to breastfeed, even if the baby eats a little bit of the drug, there is actually no harm. Antipsychotics have no effect on male sperm, so there is no need to worry. The fetus is in the mother’s stomach, and the father to take drugs or not, of course, even less relevant. 9. Mental illnesses have a strong genetic predisposition. However, taking or not taking psychotropic drugs has nothing to do with the inheritance of mental illness. The heritability of schizophrenia, may be as high as 10-28%. Moreover, the heredity or non-heredity of the disease has nothing to do with the period of onset of the disease, or whether the disease is good or bad, or whether one takes medication or not. Therefore, whether to have children or not should indeed be carefully considered. By the way: even if the child is born before the onset of the disease, there is still the possibility of inheriting the disease gene. 10, antipsychotics and fetal malformation or not, there is no ‘sure’ relationship. The conclusion of the FDA is very pertinent: “For the human body, all antipsychotics have no basis for teratogenicity, and there is no basis for non-teratogenicity”. Our hospital has been open for 70 years. No female patient has ever come to us with a complaint that her fetus was deformed because of the medication. I have been practicing medicine for almost 60 years and I have never come across anything like that either. I have had a number of female patients who were conceived after taking Pentafluridine, and none of their children were deformed. However, a famous female singer, whom we all know, got pregnant without taking any medication, and her child had a harelip. This is chance! This is fate! 11, the current commonly used antidepressants SSRI, the FDA believes that it is relatively safe, can be safely applied to the period of pregnancy (recently reported that the FDA let me paroxetine has the possibility of teratogenicity, the rest have no problem). Special reminder: once delivery, depression is easy to relapse, so, depressed female patients, whether in pregnancy, or postpartum, must insist on taking antidepressants. 12, affective adjustment agents, such as lithium carbonate, sodium valproate, carbamazepine, are teratogenic. So once a manic-depressive female patient becomes pregnant, she should stop taking her medication. Interestingly, once they are pregnant, their original condition will immediately improve, even without medication, there is no problem. However, once they give birth, it is necessary to resume the application of mood modifiers immediately, otherwise, the manic-depressive disorder tends to relapse.