Dry eye in children is now becoming more common in clinical practice and is usually characterized by frequent blinking. However, in the past, it was difficult to diagnose dry eye in children because it was difficult for them to undergo and cooperate with all the tests done by adults regarding dry eye. What are the common causes of dry eye in children? 1, children’s dry eye and partiality has a lot to do with. The typical mucin deficiency disease is vitamin A deficiency, which mainly damages the conjunctival cupped cells, the destruction of the cupped cells, which cannot secrete mucus normally, also cannot form a mucus layer, affecting the tear film formation, or because of the lack of mucus can not effectively cover the lipids mixed into the tear an epithelial interface, tear film premature rupture, causing in the eye. In children, the symptoms are frequent blinking and dry eye discomfort. 2, children’s dry eye and chronic allergic conjunctivitis related. Chronic allergy carries out chronic and regular stimulation of the local immune system, eventually leading to damage to the ocular surface, especially the loss of cup cells, resulting in a lack of mucin. In addition, dry eye in children also often occurs after episodes of viral keratitis, severe acute or subacute conjunctivitis, which can lead to loss of cupped cells and release of inflammatory factors, thus causing dry eye and resulting in frequent blinking. 3, anti-inflammatory, anti-allergic and some anti-eye fatigue eye drugs for a long time. As many eye medications contain preservatives, namely benzalkonium chloride can have a toxic effect on the epithelial tissue of the eye surface. Many parents as well as doctors often think that conjunctival inflammation is not cured and increase or prolong the use of medication, but make the condition worse. Many antiophthalmic drugs contain vasoconstrictors, anti-inflammatory drugs and other ingredients, and in many families there are children with refractive problems and prolonged use of such anti-fatigue drugs, resulting in serious dry eye in some children. 4, children watching TV for a long time, writing homework can also cause dry eyes. When watching TV or writing homework for a long time, children’s transient movements are reduced and the lipid layer in the tear film becomes thinner, which leads to rapid evaporation of tears and instability of the tear film and dry eye. 5, the occurrence of children’s dry eye also can not fail to notice the physical and chemical factors. Sometimes shampoo enters the conjunctival sac when children take a bath, which is equally irritating to the eye surface. Children’s dry eye is to some extent more difficult to deal with than adult dry eye, so understanding the factors associated with children’s dry eye plays a vital role in treatment.