The prominent manifestations of depression are: restlessness, poor sleep, loss of appetite, weight loss, inability to concentrate, loss of interest in everything, and always wanting to live lightly. The treatment methods are: medication and psychotherapy. The effective method of psychological treatment is “self-reinforcement in time”. Its theoretical basis is: because of the patient’s own negative emotions and behavior constantly reinforced, will cause depression, if the opposite, and constantly timely reinforcement of their positive emotions and behavior, depression will be less and less, until disappear. Specific implementation measures are as follows: First, adhere to normal activities. Believe in your ability to complete your work tasks and your ability to do your household chores. As long as you persist, your mood will not be increasingly depressed. Second, set a plan to leave room. Every night before going to bed, consider what you will do tomorrow. The plan should not be set too high, nor too low, leaving sufficient room for maneuver. So that every day can successfully complete the plan. Third, timely affirmation of themselves. Every night before going to bed, to fully affirm their achievements and progress during the day, do not want to negative things, can write a good diary best, good experiences, progress, achievements to the diary. Keep a diary like this every day, and feel that life will become more and more interesting. Fourth, do not talk about negative things to friends and relatives. Friends and relatives also do not listen to the negative talk of the patient. This is not a lack of sympathy for the patient, but mainly because friends and relatives listening to the patient talk about negative things will reinforce them to talk about negative topics and cause bad feelings in the patient.