Combined bilirubin in human body is excreted into the intestine through the biliary tract, and under the action of intestinal bacteria, fecal bilirubinogen is produced, most of which is excreted in the stool, while a small portion is absorbed into the blood by the intestine and finally excreted in the urine through the kidneys, which is called urobilinogen. Urobilinogen in normal people is negative or weakly positive, and the quantification is 0.3-3.55μmol/L for adult men and 0-2.64μmol/L for adult women. 3.2μmol/L is the result of the quantitative test of urobilinogen, which is basically in the normal reference range, and if there are no other abnormal indicators, there is no need to worry. Clinical causes of high urobilinogen include damage to liver cells, destruction of red blood cells due to hemolytic jaundice, and cardiac insufficiency. Urobilinogen deterministic test is commonly used for the differential diagnosis of hemolytic jaundice, hepatocellular jaundice, and obstructive jaundice. Generally, the specific condition cannot be clarified by one indicator of urobilinogen alone, so clinical symptoms and signs as well as liver function and imaging tests are needed to further rule out the presence of obstructive jaundice, such as bile duct stones, bile duct cancer, cancer of the head of the pancreas, and peri-potbelly cancer. If the test results suggest only high urobilinogen, improvements can be made through lifestyle changes, such as smoking less, drinking less alcohol, drinking more water, and trying not to eat spicy and irritating foods.